The Mesh Size Mystery: Why Particle Size Distribution (PSD) Matters More Than Just Average Micron

 

Many procurement managers focus solely on the label—buying PH101 or PH102 based on the average particle size. However, the true secret to tablet consistency lies in the Particle Size Distribution (PSD).

Why the “Span” Matters:

  • Flowability: If the distribution is too wide (too many “fines”), your powder will bridge in the hopper, causing uneven tablet weights.

  • Content Uniformity: A tight PSD ensures that your API (Active Pharmaceutical Ingredient) stays evenly blended with the MCC, preventing segregation during high-speed compression.

SenoinfiTech’s Edge: 

We don’t just measure the average; we control the D10, D50, and D90 values using laser diffraction technology. This precision ensures that every batch of SenoinfiTech MCC performs identically on your production line, reducing downtime and waste.

 

PSD